As previously announced, the SEHA - Gazprom League Quarter-Final matches will be held in August, just a few days before the SEHA Final 4 tournament. However, there was an update in schedule, regarding the matches between Nexe and Telekom Veszprem, so the new schedule for the Quarter-Final is following:

Saturday, August 21st 2021
Eurofarm Pelister – Meshkov Brest

Monday, August 23rd 2021
Nexe - Telekom Veszprem
 
Tuesday, August 24th 2021
Tatran Presov – Motor Zaporozhye

Thursday, August 26th, 2021
Vardar 1961 – PPD Zagreb

Telekom Veszprem – Nexe

Sunday, August 29th 2021
Motor Zaporozhye - Tatran Presov

Meshkov Brest – Eurofarm Pelister
 
Tuesday, August 31st 2021
PPD Zagreb – Vardar 1961